Search results for "Research network"

showing 9 items of 9 documents

Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research

2019

On behalf of TerCel

0301 basic medicineCancer ResearchResearch groupsBiomedical ResearchAllogeneic cellImmunologyCell- and Tissue-Based TherapyResearch networkTranslational researchStem cellsRegenerative MedicineCell therapyTranslational Research Biomedical03 medical and health sciences0302 clinical medicinePolitical scienceAgency (sociology)Immunology and AllergyHumansProduct (category theory)Intersectoral CollaborationGenetics (clinical)TransplantationMedical educationGovernmentBiología celularTranslational medicineNeurodegenerative DiseasesCell BiologyClinical trial030104 developmental biologyOncologyImmune System DiseasesCardiovascular DiseasesSpain030220 oncology & carcinogenesisRegenerative medicineTranslational medicine
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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The Challenge of a Place-and Network-based Approach to Development in Italian Regions

2016

Abstract This paper investigates the role of research networks inside local development processes to increase the competitiveness of underdeveloped territories. This paper, within the scope of local development theory, aims to describe the state of the art on the regional research systems resulting largely from programs co-financed between 2000 and 2013, with which the various regions are preparing to engage in programming for the period 2014-2020. The extent of consistency between the objectives of sectorial specialization set by policies previously or currently implemented and those in the planning phase (S3) is assessed, as is their connection with existing territorial specializations at…

Engineeringmedia_common.quotation_subjectAs is0211 other engineering and technologies02 engineering and technologyPhase (combat)Consistency (database systems)Development (topology)State (polity)Specialization (functional)050602 political science & public administrationRegional scienceSmart Specialization (S3)General Materials ScienceSet (psychology)media_commonScope (project management)Management sciencebusiness.industry05 social sciencesQuadruple Helix021107 urban & regional planning0506 political scienceTechnological DistrictbusinessResearch NetworkProcedia - Social and Behavioral Sciences
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Determining a healthy reference range and factors potentially influencing PRO-C3 – A biomarker of liver fibrosis

2021

Background & Aims Progressive fibrosis has been identified as the major predictor of mortality in patients with non-alcoholic fatty liver disease (NAFLD). Several biomarkers are currently being evaluated for their ability to substitute the liver biopsy as the reference standard. Recent clinical studies in NAFLD/NASH patients support the utility of PRO-C3, a marker of type III collagen formation, as a marker for the degree of fibrosis, disease activity, and effect of treatment. Here we establish the healthy reference range, optimal sample handling conditions for both short- and long-term serum storage, and robustness for the PRO-C3 assay. Methods PRO-C3 was measured in 269 healthy volunteers…

NASH-CRN NASH Clinical Research NetworkBiopsyDiseaseAST aspartate aminotransferaseRC799-869Ethnic groupsGastroenterologyNIMBLE Non-Invasive Biomarkers of Metabolic Liver Disease (consortium)FibrosisImmunology and AllergyBody mass indexmedicine.diagnostic_testFatty liverNAS NAFLD Activity ScoreGastroenterologyDiseases of the digestive system. GastroenterologyHospitalsNPV negative predictive valueLiver biopsyBiomarker (medicine)Research Articlemedicine.medical_specialtyNAFLD non-alcoholic fatty liver diseaseADAM A Disintegrin and MetalloproteasesNASH non-alcoholic steatohepatitisReference rangeReference valuesAUROC area under the receiver operating characteristics curveInternal medicineALT alanine aminotransferaseBiopsyInternal MedicinemedicineHumansFIB-4 fibrosis-4Healthy volunteersHepatologyALP alkaline phosphatasebusiness.industryCLSI Clinical and Laboratory Standards InstituteT2DM type 2 diabetes mellitusELF™ test Enhanced Liver Fibrosis testmedicine.diseaseLITMUS Liver Investigation: Testing Marker Utility in Steatohepatitis (consortium)Collagen type IIIFibrosisPPV positive predictive valueReference standardsbusinessBody mass indexBiomarkersNon-alcoholic fatty liver disease
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Reporting guidelines for health research: protocol for a cross-sectional analysis of the EQUATOR Network Library

2019

© Author(s) (or their employer(s)) 2019.

Research ReportBiomedical ResearchCross-sectional studyeducationSpecialtyMEDLINEGuidelines as Topic03 medical and health sciences0302 clinical medicineProtocolHumansresearch reportingMedicine1506030212 general & internal medicinePublishingData abstractionMedical educationbusiness.industry1711General MedicineTransparency (behavior)AuthorshipChecklist3. Good healthReview Literature as TopicResearch NetworksResearch DesignMedical Publishing and Peer ReviewScientific CollaborationReporting GuidelinesResearch reportingCitationRaw databusinessNetwork Analysis030217 neurology & neurosurgeryBMJ Open
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Connecting the data landscape of long-term ecological studies: the SPI-Birds data hub

2021

The integration and synthesis of the data in different areas of science is drastically slowed and hindered by a lack of standards and networking programmes. Long-term studies of individually marked animals are not an exception. These studies are especially important as instrumental for understanding evolutionary and eco-logical processes in the wild. Furthermore, their number and global distribution provides a unique opportunity to assess the generality of patterns and to address broad-scale global issues (e.g. climate change).

SELECTION0106 biological sciencesZOOLOGIADatabases Factual05 Environmental Sciences:Zoology and botany: 480 [VDP]Research network01 natural scienceslong‐term studiesBehavioral EcologyData standardsmeta‐data standardsData hubComputingMilieux_MISCELLANEOUSResearch Articlesmeta‐PERSONALITYCLIMATE-CHANGEEcologyEnvironmental resource managementALTERmeta&#8208birds data standards database FAIR data long-term studies meta-data standards research networkPE&RCGedragsecologieChemistryGeographyinternational[SDE]Environmental Sciences1181 Ecology evolutionary biologyPOPULATIONSPlan_S-Compliant_OALife Sciences & Biomedicinelong‐Research ArticleCLUTCH-SIZELong-term studiesEnvironmental Sciences & EcologyAnimal Breeding and GenomicsZoologi15.- Proteger restaurar y promover la utilización sostenible de los ecosistemas terrestres gestionar de manera sostenible los bosques combatir la desertificación y detener y revertir la degradación de la tierra y frenar la pérdida de diversidad biológica010603 evolutionary biologyBirdsDatabase07 Agricultural and Veterinary Sciencesddc:570VDP::Mathematics and natural scienses: 400::Zoology and botany: 480AnimalsFokkerij en Genomica:Zoologiske og botaniske fag: 480 [VDP]BiologyEcology Evolution Behavior and SystematicsMeta-data standardsMetadataFAIR dataScience & Technologylong&#8208business.industry010604 marine biology & hydrobiology06 Biological Sciences15. Life on landdatabase ; meta-data standards ; long-term studies ; birds ; data standards ; FAIR data ; research networkEVOLUTIONTerm (time)13. Climate actionResearch councilVDP::Matematikk og naturvitenskap: 400::Zoologiske og botaniske fag: 480Animal Science and Zoologyterm studiesGREAT TITSbusinessZoologybirds ; data standards ; database ; FAIR data ; long-term studies ; meta-data standards ; research networkRESPONSES
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The challenge of a place-based and network approach to the development in the territories

2016

This paper investigates the role of research networks inside local development processes to increase the competitiveness of underdeveloped territories. This paper, within the scope of local development theory, aims to describe the state of the art on the regional research systems resulting largely from programs co-financed between 2000 and 2013, with which the various regions are preparing to engage in programming for the period 2014-2020. The extent of consistency between the objectives of sectorial specialization set by policies previously or currently implemented and those in the planning phase (S3) is assessed, as is their connection with existing territorial specializations at a region…

Smart Specialization (S3) Technological District Research Network Quadruple HelixQuadruple HelixTechnological DistrictSettore SECS-P/02 Politica EconomicaSmart Specialization (S3)Settore SECS-P/06 - Economia ApplicataResearch Network
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LA COMPLESSA STRADA VERSO L’INNOVAZIONE NEI TERRITORI

2015

This paper provides a framework on regional research systems, through which, different regions are preparing to engage in program- ming period 2014 – 2020. It will also cover the regions’ investments in the co-financed programs between 2000 and 2013. Particular attention is dedicated to those projects that, in the specific objectives or specific actions have referred to high-tech districts, techno- logical platforms, clusters, innovation centers, science or technology parks and networks. It then carries out two verifications: firstly, of the degree of consistency between policies and implementation and ongoing design (S3) and secondly of their connection with the existing territorial specia…

Smart Specialization (S3) Technological District Research Network Quadruple HelixQuadruple HelixTechnological DistrictSmart Specialization (S3)lcsh:HT101-395Research Networklcsh:Urban groups. The city. Urban sociologyLaborEst
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Impact des pratiques agricoles sur l’état biologique des sols: Quelles recommandations et pistes de R&D en matière de pilotage biologique des sols

2018

National audience

[SDE] Environmental Sciencessolbiological managementparticipative research networksréseaux de recherche participativesoilbioindicateursmonitoringoutils d’aide à la décisionbioindicators[SDE]Environmental Sciencesdecision toolspilotage biologiqueComputingMilieux_MISCELLANEOUS
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